Sylvain Winkel studied medicine at the Gemeentelijke Universiteit in Amsterdam (now known as the University of Amsterdam), where he received a doctoral degree in 1902. He became a family doctor, working in Termunten at first and later in Rotterdam. Sylvain Winkel was married to Saartje Rippe. They had two children, Siegfried en Henderina, who lived elsewhere.
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In addition, a Jokos file (number 10329) on this household is at the Amsterdam Municipal Archive. Access is subject to authorization from the Stichting Joods Maatschappelijk Werk.The Jokos file reveals that a claim was lodged for compensation for valuables surrendered to the Lippmann-Rosenthal looting bank (L-claim, number 13013/15642).